Molecular and cellular mechanisms of HIF prolyl hydroxylase inhibitors in clinical trials - Chemical Science (RSC Publishing)
![PHD proteins play a key role in regulating hypoxia inducible factor... | Download Scientific Diagram PHD proteins play a key role in regulating hypoxia inducible factor... | Download Scientific Diagram](https://www.researchgate.net/publication/344117190/figure/fig1/AS:984554873561089@1611747582505/PHD-proteins-play-a-key-role-in-regulating-hypoxia-inducible-factor-HIF-stability-and.png)
PHD proteins play a key role in regulating hypoxia inducible factor... | Download Scientific Diagram
![Overview of PHD/HIF signaling. Under normoxia, both HIF-1α and HIF-2α... | Download Scientific Diagram Overview of PHD/HIF signaling. Under normoxia, both HIF-1α and HIF-2α... | Download Scientific Diagram](https://www.researchgate.net/publication/233973055/figure/fig1/AS:196086468747270@1423762065363/Overview-of-PHD-HIF-signaling-Under-normoxia-both-HIF-1a-and-HIF-2a-are-hydroxylated-by.png)
Overview of PHD/HIF signaling. Under normoxia, both HIF-1α and HIF-2α... | Download Scientific Diagram
![Targeting hypoxia-inducible factor 1 (HIF-1) signaling with natural products toward cancer chemotherapy | The Journal of Antibiotics Targeting hypoxia-inducible factor 1 (HIF-1) signaling with natural products toward cancer chemotherapy | The Journal of Antibiotics](https://media.springernature.com/m685/springer-static/image/art%3A10.1038%2Fs41429-021-00451-0/MediaObjects/41429_2021_451_Fig1_HTML.png)
Targeting hypoxia-inducible factor 1 (HIF-1) signaling with natural products toward cancer chemotherapy | The Journal of Antibiotics
![Biomedicines | Free Full-Text | HIF-α Prolyl Hydroxylase Inhibitors and Their Implications for Biomedicine: A Comprehensive Review Biomedicines | Free Full-Text | HIF-α Prolyl Hydroxylase Inhibitors and Their Implications for Biomedicine: A Comprehensive Review](https://pub.mdpi-res.com/biomedicines/biomedicines-09-00468/article_deploy/html/images/biomedicines-09-00468-g001-550.jpg?1619266047)
Biomedicines | Free Full-Text | HIF-α Prolyl Hydroxylase Inhibitors and Their Implications for Biomedicine: A Comprehensive Review
![Prolyl hydroxylase domain inhibitors as a novel therapeutic approach against anemia in chronic kidney disease - ScienceDirect Prolyl hydroxylase domain inhibitors as a novel therapeutic approach against anemia in chronic kidney disease - ScienceDirect](https://ars.els-cdn.com/content/image/1-s2.0-S0085253817303058-gr1.jpg)
Prolyl hydroxylase domain inhibitors as a novel therapeutic approach against anemia in chronic kidney disease - ScienceDirect
![Fishes | Free Full-Text | Hypoxia Activates HIF-1α and Affects Gene Expression and Transcriptional Regulation of PHD in Tegillarca granosa Fishes | Free Full-Text | Hypoxia Activates HIF-1α and Affects Gene Expression and Transcriptional Regulation of PHD in Tegillarca granosa](https://pub.mdpi-res.com/fishes/fishes-08-00359/article_deploy/html/images/fishes-08-00359-ag-550.jpg?1689048941)
Fishes | Free Full-Text | Hypoxia Activates HIF-1α and Affects Gene Expression and Transcriptional Regulation of PHD in Tegillarca granosa
![Frontiers | Possible Role of PHD Inhibitors as Hypoxia-Mimicking Agents in the Maintenance of Neural Stem Cells' Self-Renewal Properties Frontiers | Possible Role of PHD Inhibitors as Hypoxia-Mimicking Agents in the Maintenance of Neural Stem Cells' Self-Renewal Properties](https://www.frontiersin.org/files/Articles/411375/fcell-06-00169-HTML/image_m/fcell-06-00169-g001.jpg)
Frontiers | Possible Role of PHD Inhibitors as Hypoxia-Mimicking Agents in the Maintenance of Neural Stem Cells' Self-Renewal Properties
Unlocking Cellular Adaptation: The HIF Enhancer Pathway and Its Implications in Hypoxia Response - Assay Genie
![Lack of activity of recombinant HIF prolyl hydroxylases (PHDs) on reported non-HIF substrates | eLife Lack of activity of recombinant HIF prolyl hydroxylases (PHDs) on reported non-HIF substrates | eLife](https://iiif.elifesciences.org/lax/46490%2Felife-46490-fig2-v1.tif/full/,1500/0/default.jpg)
Lack of activity of recombinant HIF prolyl hydroxylases (PHDs) on reported non-HIF substrates | eLife
![Hypoxia pathway. In normoxia, PHD (blue) hydroxylates HIF-α (green),... | Download Scientific Diagram Hypoxia pathway. In normoxia, PHD (blue) hydroxylates HIF-α (green),... | Download Scientific Diagram](https://www.researchgate.net/publication/342478578/figure/fig1/AS:908777263988744@1593680792842/Hypoxia-pathway-In-normoxia-PHD-blue-hydroxylates-HIF-a-green-which-then-binds-to.png)